BCOXIB-90 TAB
— Product

BCOXIB-90 TAB

ETORICOXIB 90MG

BCOXIB-90 TAB is a tablet of etoricoxib 90 mg, a selective COX-2 inhibitor. It is used for rheumatoid arthritis, ankylosing spondylitis, and acute gouty arthritis, where the higher dose is needed for the greater inflammatory burden of these conditions.

01

Benefits

  • The 90 mg strength is the dose established for the inflammatory arthritides, where 60 mg is often insufficient.
  • Selective COX-2 inhibition gives anti-inflammatory effect with substantially less gastroduodenal ulceration than non-selective NSAIDs.
  • Effective in acute gout, where rapid and potent anti-inflammatory action shortens the attack.
  • Once-daily dosing simplifies long-term treatment in rheumatoid arthritis and ankylosing spondylitis.
  • Does not inhibit platelet function, so it does not add to bleeding risk.
02

Side effects

Not everyone gets these. Most are mild and settle as the course finishes.

Common
  • Dizziness or headache
  • Indigestion or epigastric discomfort
  • Ankle swelling or fluid retention
  • Rise in blood pressure
Less common
  • Palpitations
  • Raised liver enzymes on testing
  • Diarrhoea or nausea
  • Skin rash or itching
Stop and get medical help if any of these occur
  • Chest pain, breathlessness, or weakness or numbness down one side
  • Black, tarry stools or vomiting of blood
  • Yellowing of the skin or eyes
  • Marked swelling of the legs or sudden weight gain
  • Widespread rash with blistering or peeling skin
03

Precautions

  • Contraindicated in established ischaemic heart disease, cerebrovascular disease, peripheral arterial disease and moderate to severe heart failure.
  • Contraindicated in uncontrolled hypertension. Cardiovascular risk rises with dose and duration, so the 90 mg strength warrants closer blood pressure monitoring than 60 mg.
  • Contraindicated in active peptic ulceration or gastrointestinal bleeding, inflammatory bowel disease, and severe hepatic or renal impairment.
  • Contraindicated in NSAID or aspirin hypersensitivity, including aspirin-sensitive asthma.
  • Contraindicated in pregnancy and breastfeeding.
  • In acute gout, use for the shortest period needed to control the attack rather than continuing at this dose long term.
  • Use with care in the elderly, in dehydration, and alongside ACE inhibitors, angiotensin receptor blockers or diuretics.