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BESCORIL 100ML SYP
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BESCORIL 100ML SYP

BROMHEXINE 4MG + GUAIPHENESIN 50MG + TERBUTALIN SUL 1.25MG

BESCORIL 100ML SYP is an oral syrup combining bromhexine 4 mg, guaiphenesin 50 mg and terbutaline sulphate 1.25 mg. It is used for productive cough with tenacious sputum and associated bronchospasm — acute and chronic bronchitis, and cough in asthma and chronic obstructive pulmonary disease — where the sputum needs loosening and the airways opening.

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01

Benefits

  • Bromhexine is a mucolytic that breaks down the mucopolysaccharide fibres in sputum, making thick secretions easier to clear.
  • Guaiphenesin is an expectorant that increases the volume and reduces the viscosity of respiratory secretions, supporting a productive cough.
  • Terbutaline is a beta-2 agonist that relaxes bronchial smooth muscle, relieving the wheeze and tightness that accompany a chest infection.
  • Opening the airways while thinning the sputum makes each cough more effective at clearing the chest.
  • The liquid form allows dose adjustment and suits patients who cannot manage tablets.
02

Side effects

Not everyone gets these. Most are mild and settle as the course finishes.

Common
  • Fine tremor, particularly of the hands
  • Palpitations or a raised heart rate
  • Nausea or stomach upset
  • Headache or restlessness
Less common
  • Muscle cramps
  • Low serum potassium with higher or repeated doses
  • Dizziness
  • Skin rash or itching
Stop and get medical help if any of these occur
  • Chest pain, or a fast or markedly irregular heartbeat
  • Worsening breathlessness or wheeze after a dose (paradoxical bronchospasm)
  • Severe muscle weakness or cramps
  • Swelling of the face, lips or tongue, or difficulty breathing
  • Coughing up blood
03

Precautions

  • Tremor and palpitations from the terbutaline are expected and usually settle; warn the patient so they are not alarmed.
  • Use with caution in ischaemic heart disease, arrhythmia, hypertension, hyperthyroidism and diabetes, where beta-agonists can worsen control.
  • Beta-agonists can lower serum potassium, particularly alongside diuretics, corticosteroids or xanthines — monitor in patients on those drugs.
  • Contraindicated in known hypersensitivity to any component, and use with care in active peptic ulcer disease because of the bromhexine.
  • Maintain a good fluid intake; mucolytics and expectorants work far better in a well-hydrated patient.
  • Not for a dry, non-productive cough — this preparation is intended to make coughing more productive, not to suppress it.
  • Reassess if cough persists beyond a week or is accompanied by fever, breathlessness or blood-stained sputum.
  • Use in pregnancy and breastfeeding only on medical advice.