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CARIMOX-CV DDS SWFR DRY SYP
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CARIMOX-CV DDS SWFR DRY SYP

AMOXY 400MG + CLAUV POTASIUM 57.0MG

CARIMOX-CV DDS SWFR DRY SYP is a double-strength dry syrup of amoxicillin 400 mg with clavulanate potassium 57 mg per dose, reconstituted before use. The higher amoxicillin-to-clavulanate ratio is designed for infections needing a larger amoxicillin dose, particularly childhood otitis media caused by resistant pneumococci.

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01

Benefits

  • The high-dose amoxicillin ratio overcomes penicillin-resistant Streptococcus pneumoniae, which lower-dose formulations do not reliably cover.
  • Clavulanate still covers the beta-lactamase-producing Haemophilus and Moraxella strains common in otitis media.
  • Raising amoxicillin without raising clavulanate proportionally means better cover with less diarrhoea.
  • Twice-daily dosing suits children and their carers.
  • The liquid form allows accurate weight-based dosing.
02

Side effects

Not everyone gets these. Most are mild and settle as the course finishes.

Common
  • Diarrhoea or loose stools
  • Nausea or vomiting
  • Abdominal discomfort
  • Skin rash
Less common
  • Oral or nappy-area thrush after the course
  • Raised liver enzymes on testing
  • Irritability or disturbed sleep
  • Surface discolouration of the teeth, which brushing removes
Stop and get medical help if any of these occur
  • Swelling of the face, lips or tongue, difficulty breathing, or collapse
  • Yellowing of the skin or eyes, or dark urine
  • Severe, watery or bloody diarrhoea during or in the weeks after the course
  • Widespread rash with blistering or peeling skin
  • Persistent vomiting, or signs of dehydration
03

Precautions

  • This is a double-strength preparation. Confirm the strength before dispensing — substituting it for the standard formulation at the same volume doubles the amoxicillin dose.
  • Contraindicated in known penicillin allergy, and in any previous amoxicillin-clavulanate-associated jaundice.
  • Reconstitute exactly to the mark with the water indicated, shake before every dose, and use the measure supplied.
  • Refrigerate after reconstitution and discard after the stated period, usually seven days.
  • Dose strictly by body weight on the prescriber's instruction.
  • Give with food to improve absorption and reduce diarrhoea.
  • Avoid in suspected infectious mononucleosis, and reduce the dose in significant renal impairment.
  • Complete the full prescribed course; never keep a part-used bottle for a future illness.