— Product

H KORT 100MG INJ

HYDROCORTISONE

H KORT 100MG INJ is an injection of hydrocortisone 100 mg, a corticosteroid given intravenously or intramuscularly. It is used in acute severe asthma, anaphylaxis as an adjunct, acute adrenal insufficiency, severe allergic reactions and acute inflammatory emergencies where rapid corticosteroid action is required.

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Benefits

Rapid onset, making it the corticosteroid of choice in acute emergencies such as severe asthma and anaphylaxis.
Hydrocortisone is identical to the body's own cortisol, which makes it the correct replacement in acute adrenal insufficiency and Addisonian crisis.
Its mineralocorticoid activity is an advantage in adrenal crisis, where salt and water retention are also needed.
Useful adjunct in anaphylaxis alongside adrenaline, reducing the risk of a late-phase reaction.
Widely used as perioperative steroid cover in patients on long-term corticosteroid therapy.

Side effects

Not everyone gets these. Most are mild and settle as the course finishes.

Common

Rise in blood glucose
Flushing of the face
Insomnia or restlessness
Increased appetite and fluid retention

Less common

Rise in blood pressure
Mood disturbance or agitation
Delayed wound healing and increased susceptibility to infection
Low serum potassium from the mineralocorticoid effect

Stop and get medical help if any of these occur

Signs of infection — fever, spreading redness, or increasing pain at an injection site
Severe abdominal pain, or black or tarry stools
Marked confusion, agitation or psychotic symptoms
Very high blood glucose with thirst, frequent urination and drowsiness
Severe breathlessness or rapid swelling of the legs

Precautions

For administration by a qualified healthcare professional only.
In anaphylaxis this is an adjunct — adrenaline remains the first-line treatment and must not be delayed to give a steroid.
Contraindicated in systemic fungal infection and in untreated infection at a proposed local injection site.
Raises blood glucose markedly; diabetic patients need close monitoring.
Has significant mineralocorticoid activity — use with caution in hypertension, heart failure and where fluid retention is a concern, and monitor potassium.
Corticosteroids mask the signs of infection and impair the response to it.
Repeated or prolonged dosing suppresses the adrenal axis; do not stop abruptly after extended use.
Live vaccines are contraindicated during and shortly after significant corticosteroid exposure.