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INDOXIME-CV DRY SYP 30ML
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INDOXIME-CV DRY SYP 30ML

CEFIXIME 50MG + POTTASSIUM CLAVUNATE 31.25MG/5ML DS

INDOXIME-CV DRY SYP 30ML is a double-strength dry syrup of cefixime 50 mg with potassium clavulanate 31.25 mg per 5 ml, reconstituted before use. It is a paediatric preparation for otitis media, sinusitis, respiratory and urinary tract infection where beta-lactamase-producing organisms are likely.

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01

Benefits

  • Clavulanate protects cefixime from beta-lactamase, covering the resistant strains common in childhood ear and sinus infection.
  • A useful second-line option in childhood infection where plain cefixime or amoxicillin has failed.
  • The liquid form allows accurate weight-based dosing.
  • Twice-daily dosing is manageable for children and their carers.
  • The dry syrup format keeps the antibiotic stable until reconstitution.
02

Side effects

Not everyone gets these. Most are mild and settle as the course finishes.

Common
  • Diarrhoea or loose stools
  • Nausea or vomiting
  • Abdominal discomfort
  • Skin rash
Less common
  • Oral or nappy-area thrush after the course
  • Raised liver enzymes on testing
  • Irritability or disturbed sleep
  • Flatulence
Stop and get medical help if any of these occur
  • Swelling of the face, lips or tongue, difficulty breathing, or collapse
  • Yellowing of the skin or eyes, or dark urine
  • Severe, watery or bloody diarrhoea during or in the weeks after the course
  • Widespread rash with blistering or peeling skin
  • Persistent vomiting, or signs of dehydration
03

Precautions

  • Contraindicated in known cephalosporin allergy; use with caution in penicillin allergy and avoid after penicillin anaphylaxis.
  • Reconstitute exactly to the mark with the water indicated, shake well before every dose, and use the measure supplied.
  • Store as directed after reconstitution and discard after the stated period.
  • Dose strictly by body weight on the prescriber's instruction.
  • Give with food to reduce diarrhoea and gastric upset.
  • Dose reduction is required in significant renal impairment.
  • Complete the full prescribed course; never keep a part-used bottle for a future illness.
  • Diarrhoea is common — maintain fluid intake and report severe or bloody diarrhoea.