Home/Products/ITROSS-200 CAPS ALU ALU
ITROSS-200 CAPS ALU ALU
— Product

ITROSS-200 CAPS ALU ALU

ITRACONAZOLE 200MG CAP

ITROSS-200 CAPS ALU ALU is a capsule of itraconazole 200 mg, a triazole antifungal. It is used for onychomycosis, extensive or resistant tinea, oral and vaginal candidiasis, and systemic mycoses such as aspergillosis and histoplasmosis.

Enquire about this product → Back to catalog
01

Benefits

  • Broad antifungal activity covering dermatophytes, Candida species and several systemic fungal pathogens.
  • Concentrates in keratin at levels far above plasma and persists there for weeks after the course ends.
  • That keratin persistence allows intermittent pulse dosing in nail infection, reducing total drug exposure.
  • Effective in nail infection, where topical treatment alone rarely succeeds.
  • Oral treatment reaches infections in sites topical antifungals cannot.
02

Side effects

Not everyone gets these. Most are mild and settle as the course finishes.

Common
  • Nausea or abdominal discomfort
  • Headache
  • Diarrhoea or constipation
  • Altered taste
Less common
  • Raised liver enzymes on testing
  • Dizziness
  • Skin rash or itching
  • Menstrual irregularity
Stop and get medical help if any of these occur
  • Yellowing of the skin or eyes, dark urine, pale stools, or persistent nausea and loss of appetite
  • Breathlessness, ankle swelling or rapid weight gain, which may indicate heart failure
  • Numbness, tingling or weakness in the hands or feet
  • Hearing loss
  • Widespread rash with blistering or peeling skin
03

Precautions

  • Contraindicated in heart failure or a history of it — itraconazole has a negative inotropic effect and can precipitate or worsen it.
  • A potent CYP3A4 inhibitor with a long list of serious interactions. Contraindicated with simvastatin, lovastatin, several antiarrhythmics, ergot alkaloids and midazolam. Check every co-prescribed drug.
  • Contraindicated in pregnancy and in women of childbearing potential not using reliable contraception; contraindicated in breastfeeding.
  • Check liver function before starting and periodically during courses longer than a month.
  • Absorption requires gastric acid — take immediately after a full meal and avoid antacids and proton pump inhibitors around the dose.
  • Nail infection needs months of treatment; visible improvement lags well behind the course.
  • Confirm the diagnosis with a nail clipping or skin scraping before committing to a long systemic antifungal course.