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MECAROSE PLUS2ML INJ +SYRNG
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MECAROSE PLUS2ML INJ +SYRNG

PYRIDOXINE HYD + METHYLCOBALAMIN + NICOTINAMIDE IP + BENZY ALCO I

MECAROSE PLUS2ML INJ +SYRNG is a 2 ml prefilled injection combining pyridoxine hydrochloride, methylcobalamin and nicotinamide, given intramuscularly. It is used in peripheral neuropathy, vitamin B12 deficiency with neurological features, and in B-vitamin deficiency where oral absorption is impaired.

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01

Benefits

  • The injectable route bypasses the gut, essential in pernicious anaemia and malabsorption where oral B12 is not absorbed.
  • Methylcobalamin is the active coenzyme form of vitamin B12, involved directly in myelin formation and nerve repair.
  • Pyridoxine and nicotinamide support nerve metabolism and energy production.
  • Corrects deficiency faster than oral supplementation where neurological symptoms are present.
  • The prefilled syringe removes dose measurement errors and suits clinic use.
02

Side effects

Not everyone gets these. Most are mild and settle as the course finishes.

Common
  • Pain or redness at the injection site
  • Flushing or warmth of the skin from the nicotinamide
  • Nausea
  • Headache
Less common
  • Itching or rash
  • Dizziness
  • Transient fall in blood pressure
  • Metallic taste
Stop and get medical help if any of these occur
  • Swelling of the face, lips or tongue, difficulty breathing, or collapse
  • Widespread rash or hives
  • Severe flushing with dizziness or fainting
  • New numbness or tingling on prolonged high-dose pyridoxine
  • Severe pain, swelling or redness at the injection site
03

Precautions

  • For administration by a qualified healthcare professional, by intramuscular injection.
  • Establish the cause of B12 deficiency before treating; pernicious anaemia requires lifelong replacement.
  • Correcting B12 deficiency can unmask hypokalaemia as red cell production resumes — monitor in severe deficiency.
  • Prolonged high-dose pyridoxine causes peripheral neuropathy; do not continue courses indefinitely without review.
  • Nicotinamide flushing is common and harmless but alarming — warn the patient.
  • Contraindicated in known hypersensitivity to any component or to benzyl alcohol, present as a preservative.
  • Contraindicated in neonates because of the benzyl alcohol content.
  • Use in pregnancy and breastfeeding only on medical advice.