— Product
MEFROS SPASS TAB B/L
MEFENAMIC ACID + DICYCLOMINE
MEFROS SPASS TAB B/L is a tablet combining mefenamic acid with dicyclomine, an NSAID paired with a smooth-muscle antispasmodic. It is used for colicky and spasmodic pain — dysmenorrhoea, intestinal colic and spasmodic abdominal pain — where relaxing the smooth muscle matters as much as blocking the pain.
01
Benefits
- Mefenamic acid is particularly effective in dysmenorrhoea, reducing both the pain and the excessive uterine contraction that causes it.
- Dicyclomine relaxes gastrointestinal and uterine smooth muscle directly, relieving the cramping component.
- The two mechanisms are complementary in period pain, which is the commonest indication.
- Mefenamic acid also reduces menstrual blood loss, an advantage in heavy periods.
- Useful in intestinal colic and in the spasmodic pain of irritable bowel syndrome.
02
Side effects
Not everyone gets these. Most are mild and settle as the course finishes.
Common
- Dry mouth
- Diarrhoea, which is more frequent with mefenamic acid
- Blurred vision
- Dizziness or drowsiness
Less common
- Nausea or epigastric discomfort
- Difficulty passing urine
- Constipation
- Fast heart rate or palpitations
Stop and get medical help if any of these occur
- Severe or persistent diarrhoea
- Black, tarry stools or vomiting of blood
- Inability to pass urine
- Severe eye pain with blurred vision and halos around lights
- Confusion or hallucinations, particularly in the elderly
- Severe abdominal pain that worsens rather than settles
03
Precautions
- Contraindicated in narrow-angle glaucoma, urinary retention, significant prostatic enlargement, myasthenia gravis, paralytic ileus and obstructive gastrointestinal disease.
- Contraindicated in active peptic ulcer disease, inflammatory bowel disease, severe hepatic or renal impairment, and NSAID hypersensitivity.
- Diarrhoea with mefenamic acid is a reason to stop rather than continue.
- Do not use to mask undiagnosed acute abdominal pain, which may need surgical assessment.
- Contraindicated in infants under six months and in breastfeeding, because of the dicyclomine.
- Causes drowsiness and blurred vision. Warn before driving.
- Use with particular caution in the elderly, who are more susceptible to confusion, urinary retention and falls.
- Avoid in the third trimester of pregnancy; limit to short courses and take with or after food.