— Product
NIMOROSS GOLD TAB
NIMESULIDE 100MG + PARACETAMOL 325MG
NIMOROSS GOLD TAB is a tablet of nimesulide 100 mg with paracetamol 325 mg. It is used for the short-term treatment of acute pain and fever — musculoskeletal injury, dental pain and febrile illness with body ache — for a maximum of fifteen days.
01
Benefits
- Nimesulide has a rapid onset of analgesia, often within fifteen to thirty minutes.
- Paracetamol adds central analgesia and antipyresis, complementing the peripheral anti-inflammatory action.
- Preferential COX-2 activity gives anti-inflammatory effect with somewhat less gastric impact than non-selective NSAIDs.
- Effective in acute musculoskeletal injury and dental pain where a fast effect matters.
- The combination provides both anti-inflammatory and antipyretic cover in a single tablet.
02
Side effects
Not everyone gets these. Most are mild and settle as the course finishes.
Common
- Nausea, indigestion or epigastric discomfort
- Diarrhoea
- Dizziness or headache
- Skin rash
Less common
- Gastric erosion or bleeding
- Raised liver enzymes on testing
- Fluid retention
- Itching or sweating
Stop and get medical help if any of these occur
- Yellowing of the skin or eyes, dark urine, pale stools, persistent nausea or loss of appetite — both components carry hepatic risk
- Black, tarry stools or vomiting of blood
- A marked fall in urine output
- Swelling of the face, lips or tongue, or difficulty breathing
- Widespread rash with blistering or peeling skin
03
Precautions
- This combination carries a double hepatic burden — nimesulide is a recognised cause of severe liver injury and paracetamol is hepatotoxic in overdose. Counsel the patient on liver symptoms and stop at the first sign.
- Restricted to a maximum of fifteen days, second-line use only.
- Contraindicated in children under twelve years.
- Contraindicated in any hepatic impairment, in a history of hepatic reaction to nimesulide, and in alcohol or drug dependence.
- Contraindicated in active peptic ulcer disease, gastrointestinal bleeding, severe renal impairment, and NSAID hypersensitivity.
- Check total daily paracetamol intake across all products — combining this with another paracetamol product compounds the liver risk.
- Contraindicated in pregnancy and breastfeeding; avoid alcohol entirely.
- Take with or after food, at the lowest effective dose for the shortest possible period.