— Product
PYRIBEST DS SYP 60ML
PARACETAMOL 250MG
PYRIBEST DS SYP 60ML is a double-strength oral suspension of paracetamol 250 mg per dose, for children. It is used for fever and mild to moderate pain in older or heavier children, where the standard 125 mg strength would require an impractically large volume.
01
Benefits
- The higher concentration delivers the required dose in a smaller volume, which older children accept more readily.
- Effective for fever, headache, post-immunisation discomfort and minor injury.
- Does not irritate the stomach or affect platelet function, unlike NSAIDs.
- Suitable where ibuprofen is contraindicated, including in asthma, dehydration and chickenpox.
- Excellent safety record in childhood when dosed correctly.
02
Side effects
Not everyone gets these. Most are mild and settle as the course finishes.
Common
- Generally very well tolerated at recommended doses
- Occasional nausea
- Mild stomach discomfort
- Skin rash in a small number of children
Less common
- Raised liver enzymes on testing
- Itching or urticaria
- Vomiting
- Hypersensitivity reaction
Stop and get medical help if any of these occur
- Any suspected overdose — even when the child appears completely well
- Yellowing of the skin or eyes, or dark urine
- Swelling of the face, lips or tongue, or difficulty breathing
- Widespread rash with blistering or peeling skin
- Fever with drowsiness, a stiff neck, a rash that does not fade under pressure, or difficulty breathing
03
Precautions
- This is a DOUBLE-STRENGTH preparation. Confirm the strength before dispensing and before every dose — giving the same volume as the 125 mg suspension delivers twice the intended dose. This is a well-recognised cause of paediatric paracetamol overdose.
- Dose strictly by body weight using the measure supplied. Never use a household spoon.
- Do not give alongside any other paracetamol-containing preparation, including cold and cough syrups.
- Never exceed the stated number of doses in 24 hours, and observe the minimum interval between doses.
- In suspected overdose, seek emergency care immediately regardless of how well the child appears.
- Reduce the dose in low body weight, malnutrition and hepatic impairment.
- A child with fever plus drowsiness, a non-blanching rash, stiff neck, fast breathing or poor feeding needs urgent assessment.
- Shake well before each dose and keep out of reach of children.